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28kHz 500W Ultrasonic Cell Disruptor for Lab

Original price was: $923.00.Current price is: $830.00.

SKU: SWP-H2850 Categories: , ,

Availability: 99 in stock (can be backordered)

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  • Premium Titanium Alloy Probe: Machined from solid, high-grade biocompatible titanium alloy (Ti-6Al-4V) to ensure ultimate mechanical strength and maximum corrosion resistance against aggressive chemical reagents.
  • Focused 28kHz Mechanical Shear: Operates at a low-frequency 28kHz sweet spot to generate intense, highly localized acoustic cavitation, perfect for disrupting tough cell walls and shearing dense samples.
  • Constant 500W Power Delivery: Backed by a high-efficiency industrial-grade transducer converter designed to maintain stable, uninterrupted energy output for heavy laboratory testing and pilot batching.
  • Automatic Frequency Tracking & Locking: Built-in microprocessor automatically scans and adjusts the running frequency, eliminating manual tuning and protecting circuits from detuning due to sample temperature or viscosity shifts.
  • Digital Amplitude Regulation (1% – 100%): Allows for linear, ultra-precise adjustment of ultrasonic intensity, protecting delicate proteins from overheating while providing raw power for nanoparticle deagglomeration.
  • Integrated Pulse & Process Timer: Features a fully programmable digital panel with flexible pulse settings (On/Off intervals) to control thermal accumulation and guarantee high operational repeatability for scientific protocols.

Compliance & Quality Standards:
✔ ISO 9001 | ✔ FCC | ✔ CE | ✔ RoHS


28kHz 500W Ultrasonic Cell Disruptor with Titanium Alloy Probe

The 28kHz 500W Ultrasonic Cell Disruptor (also known as an ultrasonic sonicators, cell disruptor, or liquid emulsifier) provides a high-intensity cavitation solution for laboratory research and pilot-scale processing. Engineered for superior liquid processing efficiency, this heavy-duty sonication system delivers intensive acoustic shear forces directly through a premium titanium probe, ensuring rapid and uniform processing for cell lysates, nano-emulsions, nanoparticle dispersion, and challenging chemical synthesis.

Built to endure demanding laboratory and industrial workloads, our 500W ultrasonic homogenizer supports stable processing under varying load conditions. Equipped with a premium, high-efficiency Titanium Alloy Probe, this system operates at 28kHz—the ideal low-frequency sweet spot for generating intense, aggressive cavitation bubbles that effortlessly disrupt tough cell walls, shear DNA, reduce particle sizes to the nanoscale, and accelerate mass transfer in chemical vats.

Smart Digital Control & Robust Acoustic Enclosure: The system is powered by an advanced microcomputer-controlled digital generator featuring automatic frequency tracking and amplitude compensation, eliminating the risk of detuning during temperature or viscosity shifts. Depending on your process setup, the compact and ergonomically designed 500W converter can be easily handheld, stand-mounted, or integrated into continuous-flow soundproofing chambers, allowing you to optimize your workspace layout with minimal acoustic interference.

The entire series features premium piezoelectric lead zirconate titanate (PZT) transducers, ensuring exceptionally high energy conversion efficiency and stable, continuous power delivery. Built to optimize modern process tracking, this digital homogenizer features a clear LCD display for power, temperature, and timer settings, supporting precise repeatability required for scientific replication and quality-controlled production lines.

Factory direct supply with stable premium quality, highly competitive wholesale pricing, and fast global shipping for laboratory researchers, biotech firms, pharmaceutical manufacturers, and chemical process engineers.


🔹 28kHz 500W Ultrasonic Homogenizer Technical Specifications

Technical specifications of 28kHz 500W ultrasonic homogenizer


🔹 Key Features of 500W Ultrasonic Cell Disruptor with Titanium Probe

  • Premium Solid Titanium Alloy Probe: Machined from high-grade biocompatible titanium alloy (Ti-6Al-4V) to offer ultimate resistance against heavy cavitation erosion, high temperatures, and corrosive chemical reagents.
  • High-Intensity 28kHz Cavitation: Operates at a powerful low-frequency 28kHz to maximize the mechanical shear force of acoustic cavitation, perfect for processing viscous liquids and tough samples.
  • Intelligent Automatic Frequency Tracking: Microprocessor-controlled digital generator automatically scans and adjusts the resonant frequency, maintaining optimal power output even as sample viscosity changes.
  • Precise Amplitude Control (1% – 100%): Digital power regulation allows for minute adjustments, ensuring delicate samples are not overheated while providing maximum energy for aggressive cell wall disruption.
  • Integrated Overload & Thermal Protection: Built-in safety sensors automatically halt ultrasonic emission in case of probe dry-running, temperature spikes, or voltage fluctuations to protect core circuits.
  • Custom Probe Diameters & Flow Cells: Available with tailor-made titanium tip sizes (replacement horns) and continuous flow-through glass/stainless steel jackets for large-volume industrial batching.

🔹 Applications & Liquid Processing Compatibility

The 28kHz 500W Ultrasonic Homogenizer is the perfect modular instrument to introduce intensive shear energy into biological, chemical, and pharmaceutical formulations. It is widely utilized across various scientific and industrial fields:

  • Biological Cell Lysis & DNA Shearing: Effortlessly breaks open plant tissues, bacteria, spores, and animal cells to extract intracellular proteins, enzymes, and intact organelles without chemical solvents.
  • Nanoparticle Dispersion & Deagglomeration: Delivers high-density localized mixing to break up agglomerates and evenly disperse carbon nanotubes, graphene, silica, and metal oxides into stable colloidal suspensions.
  • Nano-Emulsification & Homogenization: Blends immiscible liquids (like oil and water) into highly stable submicron or nano-scale emulsions for cosmetics, pharmaceuticals, and cannabis/CBD processing.
  • Sonochemical Acceleration & Extraction: Promotes chemical synthesis, catalytic reactions, and botanical extraction by accelerating mass transfer and improving compound yield via micro-jets.

🔹 What is in the Secure Packaging?

  • 1 x 500W Industrial-Grade Ultrasonic Transducer Converter (Handpiece)
  • 1 x Premium Titanium Alloy Probe (Standard Tip Installed)
  • 1 x Smart Digital Ultrasonic Generator with LED Display (Power Control Box)
  • 1 x Heavy-Duty Interconnecting Cable & Industrial Power Cord
  • 1 x Detailed Professional Operation Manual & Parameter Tuning Guide

🔹 Why Choose SIWEEP 28kHz 500W Ultrasonic Homogenizers?

  • True Continuous Duty Operation: Unlike standard laboratory sonicators that overheat quickly, our industrial-grade core and transducer housing allow for extended operational duty cycles.
  • High-Grade Ti-6Al-4V Probes: We use ultra-dense, certified titanium alloys processed with anti-wear surface treatments to minimize micro-particle shedding, preventing batch contamination.
  • Constant Amplitude Output: Smart circuit feedback locks the output amplitude, ensuring uniform processing consistency whether your fluid is thin water or thick viscous polymers.
  • Direct Factory Support: Enjoy stable professional quality, custom engineering for automated production integration, competitive wholesale pricing, and prompt global delivery.

🔹 Frequently Asked Questions

Q1: Why is 28kHz frequency better for cell disruption and homogenization compared to higher frequencies like 40kHz?

A: Lower frequencies like 28kHz create larger cavitation bubbles. When these bubbles collapse, they release significantly stronger mechanical shear forces and micro-jets than higher frequencies. This powerful mechanical shock wave is essential for breaking resilient cell walls and cracking tough polymer links.

Q2: Will the titanium probe react with acids, bases, or organic solvents in my sample?

A: Our probes are made of high-grade Titanium alloy, which has exceptional corrosion resistance against most organic solvents, mild acids, and bases. For handling extremely corrosive materials or specialized pharmaceutical applications, we can provide alternative materials or protective quartz/Teflon sleevings.

Q3: How do I prevent my delicate biological samples from overheating during sonication?

A: High-power sonication naturally generates heat in the liquid. To protect thermal-sensitive samples, we highly recommend using the built-in pulse mode (e.g., 2 seconds on, 2 seconds off) to allow cooling intervals, or placing your processing beaker inside an external ice water bath or cooling jacketed beaker.

Q4: Can I purchase different sized titanium tips for this 500W generator system?

A: Yes. The probes (horns) are detachable and replaceable. Depending on your liquid processing volume (from 10ml up to 1000ml), you can purchase different tip diameters from our store. A narrower tip provides higher intensity for smaller volumes, while a wider tip distributes power across larger volumes.

Q5: Does this 500W system support automated industrial production lines?

A: Yes, our digital smart generator supports external signal inputs. It can be equipped with communication ports (like standard 0-10V analog signals) to link with your factory PLC system, allowing automated remotely controlled start/stop and real-time amplitude tracking.


These FAQs should help you get the most out of your equipment and ensure you’re using it safely and effectively. If you have specific questions about your model, always refer to the Ultrasonic Generator User Manual or contact the manufacturer for additional guidance.

Weight12 lbs
Dimensions31.5 × 19.6 × 13.9 in

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